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Mechanical Engineering Seminar: Encapsulated Microbubbles – Michael Calvisi, UCCS
February 25 @ 4:00 pm - 5:00 pm
Prof. Michael Calvisi, University of Colorado, Colorado Springs
“Dynamics and Control of Encapsulated Ultrasound Microbubbles for Biomedicine”
Abstract: Encapsulated microbubbles (EMBs) are widely used to enhance contrast in ultrasound sonography and are emerging as powerful tools for noninvasive therapies ranging from drug and gene delivery to tumor destruction. To use EMBs effectively in biomedical applications and reduce unwanted side effects, the spherical and nonspherical oscillations of microbubbles must be controlled.
This talk discusses the use of different control schemes to optimize the acoustic driving for a specific objective, such as controlling the bubble size and frequency, or exciting shape modes to incite bubble rupture. The nonlinear control methodologies of sliding mode control and optimal control are used
Bio: Prof. Michael Calvisi joined the faculty of the Department of Mechanical and Aerospace Engineering at UCCS in 2010. He received his BS in Mechanical Engineering from the University of California, Berkeley where he later received his MS and PhD in Applied Science and Technology. He held postdoc positions at the University of Birmingham in the UK and at Northwestern. Prof. Calvisi’s research interests are in theoretical and computational fluid dynamics with an emphasis on multiphase flows and biofluid mechanics. He received the NSF CAREER Award as well as the Researcher of the Year award from the College of Engineering and Applied Science at UCCS (2017).