Proteomic Analysis of The Extracellular Matrix – From Wound Healing to Biomaterials
Alderson Hall 1613 Illinois St., Golden, CO, United StatesThe extracellular matrix (ECM) provides structural scaffolding and mediates signaling in the extracellular space. The protein component is resistant to chaotrope extraction, making proteomic characterization challenging. We have developed optimized protocols for extraction of ECM that have been refined using samples from many systems, allowing for molecular-scale assessment of ECM proteome composition and architecture. We […]